The "Shrek Running" meme originates from the 2007 animated film "Shrek the Third," where the titular character is depicted in a full-speed run. This image, often appearing as a GIF or still, symbolizes urgency, a hasty retreat, or a determined dash towards or away from something. It's frequently used to represent feeling overwhelmed, avoiding an unwanted situation, or simply being in a great hurry. Its humorous application makes it popular for expressing various scenarios requiring quick action or escape in a relatable and comical way.